Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
It is the eighth straight year that the metropolis has led Chinese cities in terms of consumer spending.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
用户说，语音信息的传输速度很快，可以在微信平台上对话。但和微软(Microsoft Corp.)的Skype等免费语音应用不同的是，在微信上还可以另选时间回复别人发来的语音信息。北京微信用户Robin Wang说，我可以决定什么时候回复，以及回不回复。
Everyone has both, but people tend to be most attached to their “best” identity — the one that offers the most social status or privileges. Successful professionals, for example, often define their identities primarily through their careers.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Adapted from an online novel Queen of No.11 Agent, the TV series is about the adventure of a female slave Chu Qiao and her romance with a prince Yan Xun.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
7. Build a reputation.
与此同时，达洛伊西奥开始环游世界，到处参加会议，并结识其他潜在的投资人。他给每一位结识的人都留下极深的印象。温布尔顿国王学院中学(King’s College School)的校长安德鲁?霍尔斯(Andrew Halls)评价道，他成熟得可怕，他在各种状况下仍保持着清晰的思维，这令我这个54岁的人都觉得惊讶。
A historically jittery commodity, crude oil has seen calm prices for three years, and one big factor has been helping smooth the wrinkles: U.S. shale oil.
Burgeoning crude supply is liable to drive prices lower in 2014 after a run of years when emerging markets supported demand, as shifting dynamics continue to change the oil landscape.
Trends and targets in antiviral phototherapy
By more than one measure, 2014 is a year the Honda Motor Co. would prefer to forget or to obscure, reflected in a roundabout way by its grand slogan for 2015, “The Year of Honda.”
200911/88512.shtmlThe price of Chinese zodiac stamps commemorating the 1980 Year of the Monkey have rocketed to a historical high for a number of reasons, according to National Business Daily.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Saving Cancer Patients in Africa
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Common 和 Day 将会演绎电影《马歇尔》中的歌曲《Stand Up For Something》还有Settle会演唱电影《马戏之王》中的歌曲《Thisis me》。
ACE2 as a potential therapeutic target for pandemic COVID-19
考夫曼和同事加雷思?哈里斯(Gareth Harris)发现，居住在那些人种快速多样化地域的英国白人更倾向于投给右翼的英国国家党(British National Party)。宾夕法尼亚大学政治学教授丹尼尔?霍普金斯(Daniel Hopkins)在美国发现了相似的民族变化导致反移民政策的规律。
Diagnostic technologies for COVID-19: a review
One of the few lots to sell significantly above its estimate, at Sotheby’s, was a 1780 landscape by Joseph Wright of Derby showing a cavern in the Gulf of Salerno with the figure of Julia, the banished daughter of Emperor Augustus.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Hope you enjoy the happiness of New Year and all the trimmings.祝你享尽新年佳节的快乐和新年的礼品。
“The individual sent an email blast to the entire staff.”
“Thutmose III was one of the most important pharaohs in Egypt’s New Kingdom and is credited with establishing the Egyptian imperial province in Canaan,” said Gabriel Barkay, the co-founder and director of the Temple Mount Sifting Project.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Song “The Spring Blossom” (Na Ying)
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Since April 2007, the value of the top 100 brands has increased by 106 per cent. That compares with a 61 per cent rise in the S&P 500 and growth of 21 per cent in the MSCI world index over the same period.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
The region boasts hundreds of miles of beaches and lakeshore, some of the country's oldest forests and waterfalls. Best of all, it offers reasonable travel costs and sees far fewer travelers than big cities.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
The IOM says fewer than 35,000 migrants, or about three percent, have crossed by land into Greece and Bulgaria from Turkey.
Antiviral drug discovery: broad-spectrum drugs from nature
3.Video Editing: 19.2 percent increase
Lawrence’s 2016 earnings dropped 11.5 percent from her 2015 total of $52 million. Forbes will release its list of the world’s highest-paid actors on Thursday. Last year Robert Downey Jr. topped the list with an estimated $80 million.
Influenza neuraminidase: A druggable target for natural products
9. The Chinese militarywill demand and receive vastly expanded investments in the form of advancedaircraft and ships.
Welcome as they were, surging sales weren't the biggest news of the year. Detroit celebrated when General Motors (GM, Fortune 500) made Mary Barra the auto industry's first female CEO, then held its breath while Ford (F, Fortune 500) CEO Alan Mulally dithered over a move to Seattle and Microsoft. The old Big Three, complaining about straining available production capacity, made plans to expand and hire. Tesla(TSLA) fired up electric car sales and refused to play by industry's rules, while Google(GOOG, Fortune 500) pioneered a car that drives itself.
10. Economics is killing the economy, but like coke addicts we won't stop
The host list of 2014 Spring Festival Gala, including Zhu Jun, Dong Qing, Bi Fujian, Li Sisi and Zhang Guoli, are released on Wednesday. Chinese film actor and director Zhang Guoli will host the annual gala of China Central Television (CCTV) for the first time.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Of the 6,527 new rentals scheduled to hit the market in Brooklyn next year, 1,442 are in Bedford-Stuyvesant, Bushwick and Clinton Hill, all considered off the beaten path not that long ago, according to data provided by Citi Habitats.
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
“…brought his dog.”
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
“That’s the difference between tweeting from your couch and governing the country. If you govern the country, you have to take sensible decisions, and that isn’t sensible,” Mr Rutte replied.
There has also always been a certain fluidity to this concept of whiteness. Irish and Italian immigrants to the United States, and Jews in Britain, were once seen as separate from the white national majority, and are now generally considered part of it, benefiting from racial privilege. At the same time, Jews’ white skin did not protect them from being cast as outsiders by some of Mr. Trump’s supporters who have circulated anti-Semitic memes on social media.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
The annual national civil service exam kicked off last Sunday, and some recent hot topics - such as college graduates starting their own businesses and the Yutu (Jade Rabbit) lunar rover - appeared in the exam questions.
开发商：Supermassive Games、Sony Computer Entertainment
5.Britons love bleak humour: that's why all the hire bikes are branded with the name of a bank currently being investigated for fixing interest rates. It's supposed to be funny.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Inhibition of SARS coronavirus helicase by bismuth complexes
(Actually, JetBlue wasn’t the absolute worst airline for departure delays the last three holiday seasons. That crown went to Comair, a regional carrier for Delta Air Lines
“We will see a lot of headlines about [emerging market export growth] picking up in the first half of 2017,” says Bhanu Baweja, head of EM cross asset strategy at UBS, who believes EM exports will show year-on-year growth of between 8 and 13 per cent in dollar terms in the first quarter of this year, “a complete postcode away” from the negative numbers currently being reported.
继Facebook前员工肖恩帕克(Sean Parker)和查马斯帕里哈皮蒂亚(Chamath Palihapitiya)——二人谴责了社交媒体的成瘾性——之后，新的一年将有更多的科技行业工作者发声。
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
During a town hall hosted by MSNBC on last Monday night, host Rachel Maddow asked Clinton whether she would match a campaign promise Canadian Prime Minister Justin Trudeau made good on earlier this year.
'For what is really exceptional, not seen on the market, there are really clients looking for such investments,'
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
I empathize with the Mavs' position. It's tough to tell your fans that all hope is lost in November, and it's especially tough when you've got a Hall of Famer still on your roster.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
排行榜的最新单曲有Shawn的《There's Nothing Holdin' Me Back》，击败DJ Khaled 的《Wild Thoughts ft. Rihanna》和Ed Sheeran的热播曲目《shape of you》，以及放了播破纪录Addy Yankee & Luis Fonsi的《Despacito》。
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
The magazine also notes that he gave $66 million to his presidential campaign and paid $25 million to settle a lawsuit related to Trump University.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Since you will be spending so much time in your office space, you should be comfortable enough to enjoy what you do. A comfy chair will keep you pleased throughout the day. We recommend the Allak Swivel Chair, $59.99, at Ikea.com. If you need music to keep your mind stirring, we recommend the Sound System iPod Speaker, $220, at UrbanOutfiters.com.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
All kinds of companies say they plan to add senior systems analysts, whose base pay is projected to rise 5% over this year's levels, to as high as $85,500; financial analysts, whose salaries will start at $81,500 at large companies, 4.8% more than in 2010; and experienced administrative assistants, at starting salaries of up to $41,750, a 3.1% increase.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
These are just some of the issues that will face New Yorkers next year. And then there’s the new drum set the neighbor’s son received for Christmas ...
4．The Mask Of Zorro
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
The first drone can be traced back to 1916 when British inventor Archibald Low designed and flew the first unmanned radio-controlled vehicle. The drone was made to counterattack German Zeppelin airships, and it also carried out ground attacks during World War I. It was made with wood and tin, its wings taken from the lower wing of another biplane. Overall, the drone was somewhat unsuccessful because the noise from its engine interfered with its radio. The Sopwith Aircraft Company also tried making a drone in 1916. They placed the radio equipment at the tail so that the engine would not interfere with its signal, but their drone never flew as it was damaged in an accident on the ground. Low would try flying his drone again in 1917 when he flew it in front of some senior military officers. It was launched from the back of a lorry and flew for some time before crashing due to engine failure, almost killing the military officers present.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
最佳录影带：Little Big Town《Tornado》
This slide in the dollar value of exports has entirely been a price effect, driven by lower commodity prices. In volume terms, emerging market exports have continued to rise since 2014, even if volume growth in year-on-year terms has moderated to around 2 per cent, a fraction of the double-digit rates witnessed either side of the global financial crisis, as the second chart shows.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
The annual national civil service exam kicked off last Sunday, and some recent hot topics - such as college graduates starting their own businesses and the Yutu (Jade Rabbit) lunar rover - appeared in the exam questions.
The U.S. is set to add nearly 3 million jobs in 2014 — the biggest increase since 1999. The burst in job creation, expected to continue in 2015, is sure to fuel consumer spending. So, too, will a plunge in gasoline prices that's given households extra cash to spare on other goods and services. See: Americans saved $14 billion as gasoline prices declined in 2014.
It's impossible to list every woman who's ever existed, this list obviously be restricted to women who've achieved a fair level of celebrity. These are the hottest women celebrities of 2015.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Such highlighted talents also include cult director David Lynch of the United States and the versatile Taiwan filmmaker Sylvia Chang, whose representative works are on the recommended lineup.
*最佳综艺节目台本创作：《约翰?奥利佛上周今夜秀》(Last Week Tonight With John Oliver)
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Cambridge Judge Business School also ends the year on a high, appearing for the first time in the rankings for both open and custom executive education, and climbing three places in the MBA ranking and 12 places in the Executive MBA table.
A modular microarray imaging system for highly specific COVID-19 antibody testing
WTF.3: I'm Bigger Than You Think
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
She said: 'Mom is like, "Oh my God, let's go and meet Ariana Grande." I'm like, "Mom, for real?"
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
According to the country's film regulator, China's box office sales have boosted a whopping 48.7 percent in the last year alone.
‘Law & Order: SVU’ This NBC ripped-from-the-soap-opera perils of Olivia (Mariska Hargitay) — psychopath rapist-stalker, tortured love affair, new baby — that took up so much air last season finally died down, and this season, the show’s 16th, the detectives got back to sex crimes à clef, including a Ray Rice-inspired episode about a star sportscaster who was seen on a surveillance camera punching the lights out of his wife.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
With its goal of universal healthcaresystem coverage by 2020, Chinais expected to transform the medicine market, becoming the second largest afterthe US.In the next five years, Chinaexpects per capita spending to grow by 70 percent.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
The average entrepreneur uses dozens of cloud-based software and apps. Zapier connects your online life and helps you build new functionality. The best part about Zapier is that you don’t have to be an API wizard to use it.
A facile assay for rapid detection of COVID-19 antibodies
The contiguous United States set a temperature record in 2012, a year of scorching heat waves and drought. But, mostly because of the unusual chill in the East, 2014 was only the 34th warmest year on record for the lower 48 states.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
“An employee packed up her belongings and walked out without a word.”
STEP 5: GET RID of most of your friends
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
会。美国政府在垂直合并案上已有数十年没赢过。据美国司法部(Department of Justice)自己的审查指导原则，像时代华纳这样的内容所有者与AT&T这样的分销商之间的“垂直合并”，远不如水平合并那么令人担忧。与此同时，Facebook、亚马逊(Amazon)、Netflix和谷歌(Google)这四巨头（合称FANG，取每家名称首字母）如今主宰了数字娱乐版图，这使得政府的如下论点更难以站住脚：两家传统媒体公司的合并，会从根本上改变竞争态势。
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
5. Hong Kong, China-A junk boat set against the famous skyline might be the iconic shot of Hong Kong, but Lonely Planet picked the territory for its natural heritage miles away from Victoria Harbor.
"It is a truly a global phenomenon in which people, due to lack of opportunities, have to leave their families behind to provide for them," said Pedro De Vasconcelos, IFAD policy advisor and author of the report.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Beck “Say Goodbye” (Capitol)
3. Deepika Padukone
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
The drama was broadcast during the summer holiday, targeting young audiences who prefer fantasies and romances.
Anti-HIV drug repurposing against SARS-CoV-2
在主张对华强硬的史蒂夫?班农(Steve Bannon)出局之后，人们就忍不住想要宣布特朗普政府的经济民族主义已死。但这忽视了唐纳德?特朗普(Donald Trump)是怎样一个人——他是一个本能的保护主义者。正如我们近来所了解到的，对于中国，他更想要的是“关税”而不是交易。他还认为打击中国是向其基础选民履行他的“美国优先”承诺的关键。
9.We here in the UK want nothing more than to provide you, our guests, with a fantastic experience this summer, combining the best in international sport, brilliant facilities, fantastic entertainment and a cultural legacy that draws on centuries of excellence in art and architecture. If you ended up with four tickets for the wrestling at the ExCel Centre, well, better luck next time.
Length-scale dependence of protein hydration-shell density
13. “Girlhood” (Céline Sciamma)
Traffic was halted along Interstate 68 in Frostburg, Maryland on Tuesday. Wet snow and high winds spinning off the edge of superstorm Sandy spread blizzard conditions over parts of West Virginia and neighboring Appalachian states.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
White anxiety has fueled this year’s political tumult in the West: Britain’s surprising vote to exit the European Union, Donald J. Trump’s unexpected capture of the Republican presidential nomination in the United States, the rise of right-wing nationalism in Norway, Hungary, Austria and Greece.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
Over at Huffington Post Mark Gongloff warns: That 'dramatic downgrade of U.S. economic growth in the first quarter revealed the economy's lingering weakness, exposed the folly of Washington's austerity obsession and slapped the Federal Reserve's newfound optimism right in the face.' And with politics deteriorating, it'll get worse.
My Sunshine is a TV drama adapted from Gu Man`s novel of the same title. It stars Wallace Chuang and Tang Yan, premiering in January, 2015. The drama depicts a man and a woman`s reunion and long-lasting romance after seven years of separation. The novel itself has been popular on the Internet and was published in 2003. Wallace Chuang soon rose to become a romantic icon among female viewers because of the role he played in the adaptation, presenting an ideal image of lover to the audiences.
About this collection
In P2P lending, borrowers are matched with investors, who are encouraged to put their money into the loans due to higher returns than they could get at state banks.
除了跳舞，玛蒂还唱歌和表演，她已经出演了电视剧《美女上错身》(Drop Dead Diva)和《奥斯汀与艾丽》(Austin & Ally)。