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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

该项目曾在2006年荣获亚军,并在2008年斩获冠军头衔。
最佳乐队组合:Little Big Town

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 综合施策破解“小微”融资难题
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

单词previous 联想记忆:
中国最高纪律监管机构日前表示,去年共有1300名涉嫌经济犯罪的外逃人员回国接受审判,其中腐败官员347人。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

A third, combined ranking lists the top 50 schools for executive education, calculated from the customised and open tables.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

中俄双方经贸合作的潜力很大,互补性很强,双方所达成的经贸关系目标是可以实现的。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Entertainer of the year: Luke Bryan
明星大撞衫 看谁更好看(二)
Seychelles
中国银行业监管机构的数据显示,去年中国商业银行的净利润总量增长了2.4%。中小银行的利润增长继续加速,而大型银行的利润增长则放慢了。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

智能皮带
不会。这笔被誉为史上最大规模的首次公开发行(IPO),是沙特实际领导人穆罕默德本萨勒曼(Mohammed bin Salman)宏大经济重组计划的基石,因此沙特阿美IPO肯定会成行。该公司的股票将在沙特本国的证交所上市。不过,此次IPO计划在国外的部分不太可能是一次公开发行。唐纳德特朗普正在为纽约游说,伦敦也在全力以赴争取。香港和东京也在沙特的考虑之中。但沙特会转而选择非公开售股,或者在晚于预期的时间在国外上市。
平均工作经验:费城班10年,旧金山班12年
The end of November is here. As I wrote Monday, recent history suggests nine teams have pretty much already been knocked out of playoff contention. Yet, none of them are straight-up tanking.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

6. How to play guitar

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

1.无论在什么情况下都不要问出租车司机,对于今年夏天伦敦的奥运会有多么激动。不是说他会勉强或尴尬地发表个人意见,而是你根本就不该问这个问题。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Henda Ayari
上个月,以美元计的中国出口跌幅显著超过预期,进口增幅也下滑一半以上。同时,对11月份数据的修正,抹去了原本疑似出现的人们长久期待的对外出口增长。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Madison Marriage is accounting and tax correspondent
It was addressed to Clark C Moore, who has since changed his name to Muhammad Siddeeq, making it hard to trace him.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Kate Winslet also won the Golden Globe for best supporting actress for a movie for her role in Steve Jobs. The actress remained in her seat looking dumbfounded after she was named best supporting actress in a film for her portrayal of Joanna Hoffman in Steve Jobs.
别提什么至少提前两周通知公司,精心安排一次离职面谈,在卷铺盖走人前费尽心机跟人搞好关系了。有些人在离职时太过匆忙,根本顾不上这些套路。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

My arms are wide open for you this New Year.我张开双臂,盼与你共度新春佳节。
社交网络公司Facebook 、电子商务巨头亚马逊和玩具公司乐高则是品牌价值增幅最大的企业。
从技术上来说,这是东盟(ASEAN)十个成员国将本地区所有贸易协议纳入一个整体框架的计划。它也没有TPP在许多方面的雄心。
中俄双方经贸合作的潜力很大,互补性很强,双方所达成的经贸关系目标是可以实现的。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

The alternative analysis is that the shift we have seen over the past three years is the beginning of a long-term structural shift which will see energy prices materially lower in real terms in the next half century than in the last. Those who take this view believe, to put it very simply, that the likely growth in supply is stronger than the growth in demand.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Although it looked like the mobile patent wars might cool off after several settlements late in 2014, this year kicked off with a skirmish between Apple and Ericsson over patent royalties related to wireless communications. BlackBerry used to be pretty litigious: It even took on celebrity Ryan Seacrest over its keyboard! But these days it is more focused on trying to convince smartphone buyers that its technology is cool again. Or at least relevant.
['?p?reit]

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

“We need to do what the mayor wants everybody to do, and that is build more housing,” said Steven Spinola, the president of the Real Estate Board of New York. However, “if the numbers don’t work, if the rent that is coming in is less than the cost of maintaining the building, then you are not going to do it.”

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Between 2015 and 2016, the US market grew by 20 per cent, while the Asian market increased by just 10 per cent. There are two ways to look at the relatively modest size of the Asian ETF market compared with both the US and Europe — which is twice as big as Asia, with $716bn in ETF assets — say analysts.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

摩根大通公司下滑至第4名,其总综合得分位居中国农业银行之后。去年名列前10强的两家欧企——荷兰皇家壳牌和汇丰控股,今年仅分别排名11名和14名。
flimsy
赖床有了新理由
Over the first weekend of 2015 the second-largest bitcoin exchange, Slovenia-based Bitstamp, was victim of a hack to the tune of some $5 million U.S. dollars’ worth of the digital currency. As the tech press were quick to point out, it was a worrisome start to the year for a digital currency that Quartz had already declared “the worst investment of 2014.” And if you look at its performance between Jan 1, 2014 and Jan. 1, 2015, that’s not wrong: bitcoin ended the year at 39% of the value it started with.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
From the themed collection: 欧盟木制家具5年内持续出口
Review Article

Influenza neuraminidase: A druggable target for natural products

11月房价环比平均下跌0.5%。
Mr. Wang, the WeChat user in Beijing, said he was an avid QQ user 11 years ago but stopped using the instant messaging service because 'it didn't look very professional.' But after downloading WeChat on his smartphone he found 'most of my colleagues and friends are on it, and everyone communicates through voicemails now.'
值得注意的是,中国电信巨头华为递交了2390项专利申请,其专利申请数量在全球企业中排名第二,仅次于飞利浦(2568项)。
8."Homeland" (2.4 million)
2002年,电视剧《绝望主妇》的制片人马克·切利正在家和他母亲看着电视。那天(以及前几天)的头条新闻是安德烈·耶茨案件审判。她因在浴缸里溺死自己的5个孩子而受审。马克转身问他母亲:"你能想象一个女人究竟是多么绝望才会杀了亲生孩子?"

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

其他机构有宝钢集团(Shanghai Baosteel Group)旗下为钢材交易商提供融资的欧冶云商(Ouyeel)、中国第六大银行招商银行(China Merchants Bank)旗下专注财富管理领域的小企业e家(Small Entrepreneur)等。
201202/172834.shtmlChinese entrepreneur Wang Xing stays in touch with a sister in California and an uncle in Australia through chat software that offers a glimpse of how China's Internet companies can compete globally.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

除了众多受过教育的劳动力可供选择,企业也被亚利桑那州的亲商监管环境所吸引,在莫卡特斯中心(Mercatus Center)发布的美国50个州商业自由度排行榜上,亚利桑那州排名第13位。这项研究援引亚利桑那州的劳动权利法、责任法和土地征用权改革作为有利条件。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

当芬兰程序员Jerry Jalava 2008年遇到车祸,他面临双重悲剧。首先,他失去了他的手指,对于靠打字生存的人来说是个大问题。其次,他必须跟一个幽默感过剩的医疗小组打交道。了解了他的遭遇后,一位外科医生竟然提议Jalava应该出门去买个“USB手指驱动器”。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

罗宾威格尔斯沃思(Robin Wigglesworth)
在经历了性骚扰丑闻频频曝光(从硅谷开始,蔓延至几乎所有行业)的一年后,女性将试图利用这一势头来推动永久性变革。鉴于科技行业的黑人和拉丁裔雇员少之又少,人们将关注被边缘化的少数族裔的困境。
这个排行榜是依据两项调查收集的数据编制的:一项调查针对参与排名的商学院,另一项针对这些商学院在3年前毕业的校友(即2013届学员)。
库尼斯在去年的榜单上排名第九。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

But that kind of emotional identification gets lost on the runway, and the retail floor. And then we are left with what?
玛多问道:"特鲁多承诺在上任之后,内阁中将有50%是女性。如今他兑现了承诺。那么你也会做出类似承诺吗?"
根据上海市统计局发布的数据显示,截止2015年年底,上海市外来常住人口数量减少至980万人,占该市大约2400万常住人口总量的40.6%。
Female founders in Silicon Valley will raise more money next year, as sexual harassment scandals have forced investors to rethink their habit of backing ventures founded by mainly young, white men. Some start-ups founded by men pursued by rumours of unsavoury pasts will not get funding, even if they are a good investment proposition.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Life's ups and downs
The average value of the household appliance sector soared 74 percent, showing the biggest increase among top 10 sectors. E-commerce and retail followed, with their value up 69 percent. The medical health care sector climbed up 32 percent. The financial service sector increased 18 percent and the alcohol sector rose 17 percent. Real estate gained 15 percent and food and drinks were up 11 percent.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 环京楼市抢房后遗症显现
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

由美国演员Jared Leto领衔的“火星三十秒”拿到了最佳另类音乐奖,同时还有Lana Del Rey,Lorde,The XX和Imanine Dragons等人提名。
The dollar value of exports from emerging market countries will rise next year for the first time since 2014, helped by higher commodity prices and modestly stronger demand, it is predicted.
科学院说:“今年的诺奖关注的是经济学的一个中心问题:如何尽可能适当地匹配不同市场主体。”
SIZE: 6,364 square feet
Harry Styles, 'Harry Styles'

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

“We do things for other reasons than a profit motive, we do things because they are right and just,” Mr Cook growled. Whether in human rights, renewable energy or accessibility for people with special needs, “I don’t think about the bloody ROI,” Mr Cook said, in the same stern, uncompromising tone that Apple employees hope they never have to hear. “Just to be very straightforward with you, if that’s a hard line for you?.?.?.?then you should get out of the stock.”
Recruits are expected to have a decent degree result — a 2.1 or above. While academic credentials are important, Teach First also looks for personal skills such as humility, respect and empathy. Applications to join the scheme outnumber the places available by seven to one.
If a sitcom that lasts for 10 years is considered popular, then surely one that still stirs up emotions after 20 must be considered a classic. Friends first aired in the US in 1994, featuring a cast of six young men and women in New York. In the time since, it’s become one of the most famous titles in the sitcom genre, aired in over 100 countries and regions in the world.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

玛戈特·瓦尔斯特伦(Margot Wallstrom)
On Her Majesty's Secret Service gets an honorable mention on our list of James Bond Theme songs.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

乔布斯在苹果全球研发者大会上手持iPhone 4 ,2010年6月7日,旧金山
In this Jan. 6, 2004 file photo, Apple CEO Steve Jobs displays the at the Macworld Conference and Expo in San Francisco. Jobs,
Blind people smile even when they have never seen someone smile.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

林怡仲预测道,下半年A股IPO的数量或将维持与上半年相当,预计2016年全年A股IPO为120宗左右,融资规模在600-800亿元人民币左右。
单词association 联想记忆:
After weeks of nail-biting auditions and five days of tense semi-finals, Britain’s Got Talent picked one of the 11 acts to be the 2014 champion.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

If the answer is "yes", then maybe you are a Type D personality.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

By more than one measure, 2014 is a year the Honda Motor Co. would prefer to forget or to obscure, reflected in a roundabout way by its grand slogan for 2015, “The Year of Honda.”

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
From the themed collection: 长沙约谈7家房产中介机构
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

pressure
Late last year, the World Health Organization declared that Zika virus was no longer a global emergency. But the disease’s effects on babies who may live for decades are only beginning to be understood. In northeastern Brazil, where links between the virus and birth defects like microcephaly were first detected, families struggle to give the best lives possible to stricken babies. Researchers hope to find clues about the virus’s effects on the fetus by studying pairs of twins in Brazil in which one was born with birth defects and the other was not.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

单词addition 联想记忆:
It has now entered the top 20 for the first time.
With all its eccentric beats and bubblegum, Number 1 Angel feels like the purest distillation of the U.K. star's pop brilliance, whether she's working with up-and-coming rapper Cupcakke on "Lipgloss" or collaborating with M? on "3AM (Pull Up)."
国际机器人联合会主席Junji Tsuda在他的《全球工业机器人市场》报告中指出,在2017年,全球约有38.7万台工业机器人售出,同比增长31%,创造了500亿美元的收入,而中国则是这一强劲增长背后的关键驱动因素之一。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

2. LinkedIn. Brand love: 47% / Rank: 309
While the S&P 500 is on track to conclude another stellar year of gains, those who sought to beat the index are poised to finish with a more dubious distinction. According to Lipper, 85% of all active stock mutual fund managers had been trailing their benchmarks through the end of November. In a typical year, there are nearly twice as many managers outperforming, with only around two thirds of funds struggling to catch up. Lipper says this is the worst year for active managers relative to the market in three decades.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 环保级木地板却无质检报告
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Beyoncé featuring Nicki Minaj “Flawless (Remix)” (Parkwood/Columbia)
新兴市场吸收的外国投资已降至金融危机以来最低水平,投资者准备迎接美国近10年来首次加息的冲击波。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

n. 泄漏

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Hunger Games star Jennifer Lawrence on Tuesday topped a Forbes magazine list of the world’s highest-paid actress for the second straight year, earning some $46 million, followed by Melissa McCarthy.
The film screens in China reached 41,179 as of the end of 2016 with another 1,612 cinemas and 9,552 film screens built during the year, according to a report by People's Daily.
6.The Conjuring 2:The Enfield Poltergeist
So I don't know what will happen in 2014--and neither does anyone else. What I imagine, though, looks like this:

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

There are 27 companies that are dropped from the list this year, including AT&T, IBM, Siemens and Xerox.
[.depri'vein]

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Or, this year, to be women with a story to tell about abuse, sexual or otherwise — a couple of whom shared #MeToo moments in our pages. Carlotta Gall told the story of Henda Ayari, a French citizen of North African heritage and anti-Salafist activist who accused a prominent Oxford professor of raping her.
在库克雄辩地捍卫平等之际,美国同性恋婚姻运动遭遇了不顺的一年,也恰逢舆论正激烈批评包括苹果在内的硅谷公司的管理者缺乏多样性,而这些管理者对美国文化具有巨大的影响力。
7. 艾米-亚当斯 1350万美元

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Joseph Keller、Raymond Goldstein、Patrick Warren和Robin Ball获此殊荣,他们的研究课题是“人类马尾辫中头发的运动及受力平衡”。
3. Portugal is entirely powered by renewable energy for four days
Chester Bennington

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Miranda Lambert “Bathroom Sink” (RCA Nashville)
It's hard to imagine LOST without Jack Shephard as the group leader. Where would the show have been without him? Had the show's writers gotten their way, we would have learned the answer to that question. When the show was pitched to ABC, Jack Shephard's character was supposed to be killed after the pilot episode, and Kate was supposed to take on more of a leadership role in the series.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 聚焦卫浴行业新词:新零售
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 建筑用非织造材料更新的超前考量
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

['k?l?nd?]
今年,我最喜欢的人物报道可能是Kiki Zhao对中国目前读者最多的诗人之一余秀华激动人心的描写。余秀华是一个了不起的人。她患有脑瘫,过去41年里大部分时间生活在农村,在一张矮桌子上写作。高中没毕业的她说自己“在能读它们(名著)之前,我就知道如何写作了”。现在,她受邀前往斯坦福大学等地,她不愿被比作艾米丽·迪金森(Emily Dickinson)。
What growth dollar exports did see among major trading partners came from shipments to the US, which rose 5.5 per cent year on year to $37.06bn. Exports to South Korea also showed growth of 8.3 per cent to $10.2bn.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

adj. 版权的
6.Jack Shephard Almost Died in the First Episode

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Except your Watson, he thinks it's hot.
The University of St Gallen’s domination of the Financial Times’ ranking of masters in management courses continues for another year.
The Magic are the single-most mystifying team in this entire exercise. They make little sense on paper or on the court.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
From the themed collection: 租房淡季 成交量却涨了
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

8. 茱莉亚-罗伯茨 1200万美元

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Such insights are of particular interest to litigation funders, who back claimants in return for a cut of damages and who try to assess the likely outcomes of disputes before committing their money. But that may have to be 2019’s breakthrough, or probably beyond.
总部位于纽约的世界品牌实验室编纂并于上周一发布了《2016世界品牌500强》榜单,苹果公司夺得了第一名的宝座。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

The post came after anonymous Internet users alleged that some questions and answers on the National Postgraduate Entrance Examination, which was held on Saturday and Sunday, were released in advance.
1.水上类比赛项目

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

荷兰合作银行是面向全球农户和农业企业的领先融资机构。
Kobe Bryant

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Like many child stars, Maddie speaks of being old before her time.
达奇斯说:星巴克在社交方面总是排名前列,2012年也不例外。公司通过社交在2012年赢得了1900万新的粉丝,它针对用户在家和出门的产品也成为用户津津乐道的谈资。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

9. The Chinese militarywill demand and receive vastly expanded investments in the form of advancedaircraft and ships.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
From the themed collection: 长城民宿惹争议 活化利用要谨慎
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

With interest rates expected to rise only slowly, commodities are likely to attract hedge funds and other speculative investors looking for juicier returns, said the bank.
今年,纽约市公寓的平均售价突破了100万美元(约合人民币623万元),这是一个影响深远的里程碑。随着城市人口的激增,错过了上一轮楼市繁荣期的社区,都见证了房价和楼盘数量的增长。
变化世界中的得与失
你可以点击此处浏览全部的假新闻,这里列出的是排名前五的假新闻:

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

祝节日快乐,新年幸福。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

Once the U.S. economic recovery started in 2009, other parts of the world started to struggle in their own ways.
日立数据系统:提升士气的狗狗节
其他评论家,如荷兰金融集团荷兰国际集团(ING)国际贸易分析主管拉乌尔?里尔宁(Raoul Leering)担心,即使从短期来看,前景也很暗淡。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

She only learnt to walk five months ago, but 'Baby Beyoncé' is already strutting her stuff on stage at pageants.
To start with, a year before the first iPhone was released, LG had introduced a full touchscreen phone. Even that was not the first, though. The world's first touchscreen phone was IBM's Simon, which was released in 1992. And touchscreen technology even predates the Simon. The first touchscreen device was a tablet made by E.A. Johnson in 1965 that was used by air traffic controllers until 1995. Bent Stumpe and Frank Beck made the first capacitive touchscreen in the early '70s. Unlike Johnson's tablet, it could not be pressed with the fingers. Instead, it required a stylus. In 1971, Samuel Hurst developed the first resistive touchscreen, which he called the "elograph." It responded to the fingers as well as a stylus. In 1985, HP invented the world's first touchscreen computer, called the HP-150. In 1993, Apple also released its first touchscreen device—the Newton Personal Digital Assistant. The product was a flop, recording low sales.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

现今和未来的科技都基于多重技术,而每一种技术都在发生着改变、并和其他技术交互。这让我们的科技产品,像是互联网的东西、电话、笔记本等等变得不稳定,这同时也让消费者感到厌恶。就说说你们手机里的应用,有多少你是真正在用的?又有多少真正能让你的生活变简单、变快捷、变得更有趣?我认为消费者对此的嘲讽情绪会上升,科技带给他们的愉悦感会被失望所取代。这会给硬件和软件的开发者造成压力,从而让他们追求最无趣的产品品质:稳定性。
n. 部分,份,命运,分担的责任

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

从碧昂丝和珍妮弗·洛佩兹的红毯着装来看,“短”是这次娱乐盛典的主题。这两位女歌手都选择及大腿的裙子来露出她们的美腿,策略性地减去领口,并注重肩膀的细节设计,但碧昂丝选择穿消防车红色从中脱颖而出,而珍妮弗·洛佩兹选择了柔和的有缎子般光泽的褐土色。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 未来浴室设计六大趋势
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Whiteness, in this context, is more than just skin color. You could define it as membership in the “ethno-national majority,” but that’s a mouthful. What it really means is the privilege of not being defined as “other.”
为什么我如此有信心东亚不会爆发战争,无论在东中国海还是南中国海?答案很简单,因为我了解推动亚洲变化的力量。虽然许多亚洲邻国会发出愤怒的民族主义声明(他们必须这样做来应对普遍的民族主义情绪),但他们的行动是谨慎和务实的。
迷你剧集/电影类最佳女配角:雷吉娜?金(Regina King),《美国重案》(American Crime)

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

China's Internet industry is often derided as a realm for knockoffs, especially of companies banned in China. Chinese search giant Baidu Inc. has a website that looks like Google Inc's. Tencent's flagship product, instant messaging service QQ, was launched in 1999 as OICQ and had similar functions to then-popular instant messaging service ICQ. Sina Corp.'s Weibo, a popular microblogging service, is invariably described as 'Twitter-like' in the Western media.
re反,treat=tract拉-拉回-撤退
There is even is a standard demagogic playbook.
Ahead of this year's fashion week, set to take place September 14 to 18, an open letter written by singer Paloma Faith and published by Peta also called for LFW and the BFC to ban animal fur.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

The online notice about the retraction lists all 107 articles and 524 authors, nearly all of whom are clinical cancer specialists from China. The hospitals named are all top public institutions.
The new numbers, reported by a tracking initiative called the Global Carbon Project and published in the journal Nature Geoscience, came on the eve of a United Nations summit meeting meant to harness fresh political ambition in tackling climate change. Scientists said the figures showed that vastly greater efforts would be needed to get long-term global warming within tolerable limits.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

For: The Los Angeles Critics Association gave it their top prize.
“An employee sent his boss a text message to say he was leaving.”
7、糟糕的肢体语言

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

英国科学家本周一证实,莱斯特市的一个停车场地下挖出的遗骸为15世纪英格兰国王理查三世,这也解开了长达五百年的谜团。
在气候学的史册里,2014年超过了2010年,成为最热的年份。有记录以来的10个最暖年份都是在1997年以后,反映了地球不断变暖的趋势,科学家说,这种变暖是人类活动的结果,并对人类文明和大自然构成了深远的长期危险。

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