Hassan's winning mark is also the fourth fastest in history for the distance, falling some 19 seconds short of the world record of 29:17.45 set by Ethiopia's Almaz Ayana at the 2016 Olympic Games in Rio.
"We have to always improve," Casemiro told reporters. "Douglas came in and did well but we'll get better as we adapt with every game," the 28-year-old added.
The Everton midfielder showed glimpses of quality, particularly in the first half, but faded before being replaced by Steven Alzate in the 74th minute at Estadio Metropolitano.
However, Kuusk's teammate Rauno Sappinen scored on 33 minutes and 61 minutes, which was followed by a penalty by Frank Liivak, lifting the hosts to 3-1 up.
"They [Ecuador] came at us without fear and it was difficult for us to play, but we were calm. In the first half we managed to get the ball back and if we had played more quickly, it would have been different, but it turned out like this, and we have to continue. It was important to get off to a winning start because all matches are going to be tough," he added.
Starting from pole position in a race he needed to win to eat into Hamilton's championship lead, Bottas held off the Briton in the opening stages but lost the lead after locking a wheel on lap 13, before pulling off six laps later for his first retirement of the season.
"This year we have a third of the usual number. However, we are sure that those who come will reach the finish line with the same wide smile and the competition will give them the same joy as in recent years," said competition director Arpad Kocsis before the start.
"We are not a strong side. After playing such an intense game, we can improve in mentality and carrying out tactics," Wuhan coach Li Xin commented. Enditem
"I don't have much to say but that I was completely overplayed by Rafa, by a better player on the court," said Djokovic in the post-match conference.
Uruguay's next qualifier will be against Ecuador in Quito on Tuesday. Enditem
Valverde has become indispensable for Real Madrid this season, starting in three of the team's four La Liga matches and blossoming in a box-to-box role.